Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation

• Marino Convertino ,

  ¶‡ These authors are co-first authors on this work.

  Affiliation Biochemistry and Biophysics Department, University of North Carolina, 120 Mason Farm Road, Chapel Hill, NC, United States of America, 27599

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• Alexander Samoshkin ,

  ¶‡ These authors are co-first authors on this work.

  Affiliation Alan Edwards Centre for Research on Pain, McGill University, 740 Dr. Penfield Avenue, Montreal, Quebec, Canada, H3A 0G1

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• Chi T. Viet,

  Affiliation Bluestone Center for Clinic Research, New York University, New York, NY, United States of America, 10010

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• Josee Gauthier,

  Affiliation Center for Pain Research and Innovation, University of North Carolina, 385 S. Columbia Street, Chapel Hill, NC, United States of America, 27599

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• Steven P. Li Fraine,

  Affiliation Department of Physiology and Cell Information Systems, McGill University, 3649 Promenade Sir William Osler, Montreal, Quebec, Canada, H3G 0B1

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• Reza Sharif-Naeini,

  Affiliation Department of Physiology and Cell Information Systems, McGill University, 3649 Promenade Sir William Osler, Montreal, Quebec, Canada, H3G 0B1

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• Brian L. Schmidt,

  Affiliation Bluestone Center for Clinic Research, New York University, New York, NY, United States of America, 10010

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• William Maixner ,

  * E-mail: dokh@unc.edu (NVD); luda.diatchenko@mcgill.ca (LD); bill_maixner@dentistry.unc.edu (WM)

  Affiliation Center for Pain Research and Innovation, University of North Carolina, 385 S. Columbia Street, Chapel Hill, NC, United States of America, 27599

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• Luda Diatchenko ,

  * E-mail: dokh@unc.edu (NVD); luda.diatchenko@mcgill.ca (LD); bill_maixner@dentistry.unc.edu (WM)

  Affiliation Alan Edwards Centre for Research on Pain, McGill University, 740 Dr. Penfield Avenue, Montreal, Quebec, Canada, H3A 0G1

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• Nikolay V. Dokholyan

  * E-mail: dokh@unc.edu (NVD); luda.diatchenko@mcgill.ca (LD); bill_maixner@dentistry.unc.edu (WM)

  Affiliations Biochemistry and Biophysics Department, University of North Carolina, 120 Mason Farm Road, Chapel Hill, NC, United States of America, 27599, Center for Pain Research and Innovation, University of North Carolina, 385 S. Columbia Street, Chapel Hill, NC, United States of America, 27599

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