Toll-Like Receptor 2 Targeted Rectification of Impaired CD8+ T Cell Functions in Experimental Leishmania donovani Infection Reinstates Host Protection

Open Access

Peer-reviewed

Research Article

Toll-Like Receptor 2 Targeted Rectification of Impaired CD8⁺ T Cell Functions in Experimental Leishmania donovani Infection Reinstates Host Protection

Syamdas Bandyopadhyay,

Affiliation The Division of Molecular Medicine, Bose Institute, Kolkata, India
⨯
Santanu Kar Mahapatra,

Affiliation The Division of Molecular Medicine, Bose Institute, Kolkata, India
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Bidisha Paul Chowdhury,

Affiliation The Division of Molecular Medicine, Bose Institute, Kolkata, India
⨯
Mukesh Kumar Jha,

Affiliation National Centre for Cell Science, Ganeshkhind, Pune, India
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Shibali Das,

Affiliation The Division of Molecular Medicine, Bose Institute, Kolkata, India
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Kuntal Halder,

Affiliation The Division of Molecular Medicine, Bose Institute, Kolkata, India
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Suchandra Bhattacharyya Majumdar,

Affiliation The Division of Molecular Medicine, Bose Institute, Kolkata, India
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Bhaskar Saha,

Affiliation National Centre for Cell Science, Ganeshkhind, Pune, India
⨯
Subrata Majumdar

* E-mail: subrata@jcbose.ac.in

Affiliation The Division of Molecular Medicine, Bose Institute, Kolkata, India
⨯

T cells
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Cytotoxic T cells
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Leishmania donovani
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Transcription factors
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Immune receptor signaling
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MAPK signaling cascades
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Parasitic diseases
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Macrophages
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