A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb’s Release from 7SK snRNP

Cong Wang; Shuiyuan Yang; Huasong Lu; Hongchao You; Man Ni; Wenjun Shan; Ting Lin; Xiang Gao; Haifeng Chen; Qiang Zhou; Yuhua Xue

doi:10.1371/journal.pone.0142739

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Peer-reviewed

Research Article

A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb’s Release from 7SK snRNP

Cong Wang ,

Contributed equally to this work with: Cong Wang, Shuiyuan Yang

Affiliation School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Shuiyuan Yang ,

Contributed equally to this work with: Cong Wang, Shuiyuan Yang

Affiliation School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Huasong Lu,

Affiliations School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America
⨯
Hongchao You,

Affiliation School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Man Ni,

Affiliation School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Wenjun Shan,

Affiliation School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Ting Lin,

Affiliation School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Xiang Gao,

Affiliation School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Haifeng Chen,

Affiliation School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯
Qiang Zhou,

Affiliations School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States of America
⨯
Yuhua Xue

* E-mail: xueyuhua@xmu.edu.cn

Affiliation School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, China
⨯

A Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb’s Release from 7SK snRNP

Cong Wang,
Shuiyuan Yang,
Huasong Lu,
Hongchao You,
Man Ni,
Wenjun Shan,
Ting Lin,
Xiang Gao,
Haifeng Chen,
Qiang Zhou

Published: November 16, 2015
https://doi.org/10.1371/journal.pone.0142739

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