Psychostimulant-Induced Testicular Toxicity in Mice: Evidence of Cocaine and Caffeine Effects on the Local Dopaminergic System

Candela R. González; Betina González; María E. Matzkin; Javier A. Muñiz; Jean Lud Cadet; Edgar Garcia-Rill; Francisco J. Urbano; Alfredo D. Vitullo; Veronica Bisagno

doi:10.1371/journal.pone.0142713

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Peer-reviewed

Research Article

Psychostimulant-Induced Testicular Toxicity in Mice: Evidence of Cocaine and Caffeine Effects on the Local Dopaminergic System

Candela R. González ,

Contributed equally to this work with: Candela R. González, Betina González

Affiliation Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
⨯
Betina González ,

Contributed equally to this work with: Candela R. González, Betina González

Affiliation Instituto de Investigaciones Farmacológicas (Universidad de Buenos Aires–Consejo Nacional de Investigaciones Científicas y Técnicas), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
⨯
María E. Matzkin,

Affiliation Instituto de Biología y Medicina Experimental (Universidad de Buenos Aires–Consejo Nacional de Investigaciones Científicas y Técnicas), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
⨯
Javier A. Muñiz,

Affiliation Instituto de Investigaciones Farmacológicas (Universidad de Buenos Aires–Consejo Nacional de Investigaciones Científicas y Técnicas), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
⨯
Jean Lud Cadet,

Affiliation NIDA Intramural Program, Molecular Neuropsychiatry Research Branch. Baltimore, Maryland, United States of America
⨯
Edgar Garcia-Rill,

Affiliation Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
⨯
Francisco J. Urbano,

Affiliation Laboratorio de Fisiología y Biología Molecular, Instituto de Fisiología, Biología Molecular y Neurociencias (Universidad de Buenos Aires–Consejo Nacional de Investigaciones Científicas y Técnicas), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
⨯
Alfredo D. Vitullo,

Affiliation Centro de Estudios Biomédicos, Biotecnológicos, Ambientales y Diagnóstico (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
⨯
Veronica Bisagno

* E-mail: vbisagno@ffyb.uba.ar

Affiliation Instituto de Investigaciones Farmacológicas (Universidad de Buenos Aires–Consejo Nacional de Investigaciones Científicas y Técnicas), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
⨯

Psychostimulant-Induced Testicular Toxicity in Mice: Evidence of Cocaine and Caffeine Effects on the Local Dopaminergic System

Candela R. González,
Betina González,
María E. Matzkin,
Javier A. Muñiz,
Jean Lud Cadet,
Edgar Garcia-Rill,
Francisco J. Urbano,
Alfredo D. Vitullo,
Veronica Bisagno

Published: November 11, 2015
https://doi.org/10.1371/journal.pone.0142713

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Seminiferous tubules
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