Performance of Droplet Digital PCR in Non-Invasive Fetal RHD Genotyping - Comparison with a Routine Real-Time PCR Based Approach

Iveta Svobodová; Eva Pazourková; Aleš Hořínek; Michaela Novotná; Pavel Calda; Marie Korabečná

doi:10.1371/journal.pone.0142572

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Peer-reviewed

Research Article

Performance of Droplet Digital PCR in Non-Invasive Fetal RHD Genotyping - Comparison with a Routine Real-Time PCR Based Approach

Iveta Svobodová ,

Contributed equally to this work with: Iveta Svobodová, Eva Pazourková

Affiliation Institute for Biology and Medical Genetics, First Faculty of Medicine, Charles University in Prague and General Faculty Hospital in Prague, Czech Republic
⨯
Eva Pazourková ,

Contributed equally to this work with: Iveta Svobodová, Eva Pazourková

Affiliation Department of Nephrology, First Faculty of Medicine, Charles University in Prague and General Faculty Hospital in Prague, Czech Republic
⨯
Aleš Hořínek ,

¶‡ Aleš Hořínek and Marie Korabečná contributed equally to this work. Michaela Novotná and Pavel Calda also contributed equally to this work.

Affiliation Institute for Biology and Medical Genetics, First Faculty of Medicine, Charles University in Prague and General Faculty Hospital in Prague, Czech Republic
⨯
Michaela Novotná ,

¶‡ Aleš Hořínek and Marie Korabečná contributed equally to this work. Michaela Novotná and Pavel Calda also contributed equally to this work.

Affiliation Department of Obstetrics and Gynecology, First Faculty of Medicine and General Faculty Hospital in Prague, Charles University in Prague, Czech Republic
⨯
Pavel Calda ,

¶‡ Aleš Hořínek and Marie Korabečná contributed equally to this work. Michaela Novotná and Pavel Calda also contributed equally to this work.

Affiliation Department of Obstetrics and Gynecology, First Faculty of Medicine and General Faculty Hospital in Prague, Charles University in Prague, Czech Republic
⨯
Marie Korabečná

* E-mail: marie.korabecna@lf1.cuni.cz

¶‡ Aleš Hořínek and Marie Korabečná contributed equally to this work. Michaela Novotná and Pavel Calda also contributed equally to this work.

Affiliation Institute for Biology and Medical Genetics, First Faculty of Medicine, Charles University in Prague and General Faculty Hospital in Prague, Czech Republic
⨯

Performance of Droplet Digital PCR in Non-Invasive Fetal RHD Genotyping - Comparison with a Routine Real-Time PCR Based Approach

Iveta Svobodová,
Eva Pazourková,
Aleš Hořínek,
Michaela Novotná,
Pavel Calda,
Marie Korabečná

Published: November 12, 2015
https://doi.org/10.1371/journal.pone.0142572

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Pregnancy
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DNA replication
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Blood plasma
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Genotyping
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