Imaging Sites of Inhibition of Proteolysis in Pathomimetic Human Breast Cancer Cultures by Light-Activated Ruthenium Compound

Suelem D. Ramalho; Rajgopal Sharma; Jessica K. White; Neha Aggarwal; Anita Chalasani; Mansoureh Sameni; Kamiar Moin; Paulo C. Vieira; Claudia Turro; Jeremy J. Kodanko; Bonnie F. Sloane

doi:10.1371/journal.pone.0142527

Loading metrics

Open Access

Peer-reviewed

Research Article

Imaging Sites of Inhibition of Proteolysis in Pathomimetic Human Breast Cancer Cultures by Light-Activated Ruthenium Compound

Suelem D. Ramalho,

Affiliation Department of Chemistry, Federal University of São Carlos, São Carlos, São Paulo, Brazil
⨯
Rajgopal Sharma,

Affiliation Department of Chemistry, Wayne State University, Detroit, Michigan, United States of America
⨯
Jessica K. White,

Affiliation Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
⨯
Neha Aggarwal,

Affiliation Department of Physiology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Anita Chalasani,

Affiliation Department of Pharmacology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Mansoureh Sameni,

Affiliation Department of Pharmacology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Kamiar Moin,

Affiliations Department of Pharmacology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America, Department of Oncology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Paulo C. Vieira,

Affiliation Department of Chemistry, Federal University of São Carlos, São Carlos, São Paulo, Brazil
⨯
Claudia Turro,

Affiliation Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
⨯
Jeremy J. Kodanko ,

* E-mail: bsloane@med.wayne.edu (BFS); jkodanko@chem.wayne.edu (JJK)

Affiliation Department of Chemistry, Wayne State University, Detroit, Michigan, United States of America
⨯
Bonnie F. Sloane

* E-mail: bsloane@med.wayne.edu (BFS); jkodanko@chem.wayne.edu (JJK)

Affiliations Department of Pharmacology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America, Department of Oncology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯

Imaging Sites of Inhibition of Proteolysis in Pathomimetic Human Breast Cancer Cultures by Light-Activated Ruthenium Compound

Suelem D. Ramalho,
Rajgopal Sharma,
Jessica K. White,
Neha Aggarwal,
Anita Chalasani,
Mansoureh Sameni,
Kamiar Moin,
Paulo C. Vieira,
Claudia Turro,
Jeremy J. Kodanko

Published: November 12, 2015
https://doi.org/10.1371/journal.pone.0142527

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Proteolysis
Is the Subject Area "Proteolysis" applicable to this article?

Thanks for your feedback.
Breast tumors
Is the Subject Area "Breast tumors" applicable to this article?

Thanks for your feedback.
Artificial light
Is the Subject Area "Artificial light" applicable to this article?

Thanks for your feedback.
Visible light
Is the Subject Area "Visible light" applicable to this article?

Thanks for your feedback.
NMR spectroscopy
Is the Subject Area "NMR spectroscopy" applicable to this article?

Thanks for your feedback.
Acetones
Is the Subject Area "Acetones" applicable to this article?

Thanks for your feedback.
Ruthenium
Is the Subject Area "Ruthenium" applicable to this article?

Thanks for your feedback.