Gene Expression Profiles from Disease Discordant Twins Suggest Shared Antiviral Pathways and Viral Exposures among Multiple Systemic Autoimmune Diseases

Lu Gan; Terrance P. O’Hanlon; Zhennan Lai; Rick Fannin; Melodie L. Weller; Lisa G. Rider; John A. Chiorini; Frederick W. Miller

doi:10.1371/journal.pone.0142486

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Peer-reviewed

Research Article

Gene Expression Profiles from Disease Discordant Twins Suggest Shared Antiviral Pathways and Viral Exposures among Multiple Systemic Autoimmune Diseases

Lu Gan,

Affiliation Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
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Terrance P. O’Hanlon,

Affiliation Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Zhennan Lai,

Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
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Rick Fannin,

Affiliation Microarray Core, Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
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Melodie L. Weller,

Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
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Lisa G. Rider,

Affiliation Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
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John A. Chiorini,

Affiliation Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
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Frederick W. Miller

* E-mail: millerf@mail.nih.gov

Affiliation Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Gene Expression Profiles from Disease Discordant Twins Suggest Shared Antiviral Pathways and Viral Exposures among Multiple Systemic Autoimmune Diseases

Lu Gan,
Terrance P. O’Hanlon,
Zhennan Lai,
Rick Fannin,
Melodie L. Weller,
Lisa G. Rider,
John A. Chiorini,
Frederick W. Miller

Published: November 10, 2015
https://doi.org/10.1371/journal.pone.0142486

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