Dual Action of miR-125b As a Tumor Suppressor and OncomiR-22 Promotes Prostate Cancer Tumorigenesis

William T. Budd; Sarah J. Seashols-Williams; Gene C. Clark; Danielle Weaver; Valerie Calvert; Emanuel Petricoin; Ema A. Dragoescu; Katherine O’Hanlon; Zendra E. Zehner

doi:10.1371/journal.pone.0142373

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Peer-reviewed

Research Article

Dual Action of miR-125b As a Tumor Suppressor and OncomiR-22 Promotes Prostate Cancer Tumorigenesis

William T. Budd,

Current address: American International Biotechnology, Richmond, Virginia, United States of America

Affiliation Department of Biochemistry and Molecular Biology, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Sarah J. Seashols-Williams,

Affiliations Department of Biochemistry and Molecular Biology, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States of America, Department of Forensic Science, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Gene C. Clark,

Affiliation Department of Biochemistry and Molecular Biology, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Danielle Weaver,

Affiliation Center for the Study of Biological Complexity, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Valerie Calvert,

Affiliation Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia, United States of America
⨯
Emanuel Petricoin,

Affiliation Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, Virginia, United States of America
⨯
Ema A. Dragoescu,

Affiliation Department of Pathology, VCU Medical Center, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Katherine O’Hanlon,

Affiliation American International Biotechnology, Richmond, Virginia, United States of America
⨯
Zendra E. Zehner

* E-mail: zendra.zehner@vcuhealth.org

Affiliation Department of Biochemistry and Molecular Biology, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯

Dual Action of miR-125b As a Tumor Suppressor and OncomiR-22 Promotes Prostate Cancer Tumorigenesis

William T. Budd,
Sarah J. Seashols-Williams,
Gene C. Clark,
Danielle Weaver,
Valerie Calvert,
Emanuel Petricoin,
Ema A. Dragoescu,
Katherine O’Hanlon,
Zendra E. Zehner

Published: November 6, 2015
https://doi.org/10.1371/journal.pone.0142373

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