IMGT/HighV-QUEST Statistical Significance of IMGT Clonotype (AA) Diversity per Gene for Standardized Comparisons of Next Generation Sequencing Immunoprofiles of Immunoglobulins and T Cell Receptors

Safa Aouinti; Dhafer Malouche; Véronique Giudicelli; Sofia Kossida; Marie-Paule Lefranc

doi:10.1371/journal.pone.0142353

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Research Article

IMGT/HighV-QUEST Statistical Significance of IMGT Clonotype (AA) Diversity per Gene for Standardized Comparisons of Next Generation Sequencing Immunoprofiles of Immunoglobulins and T Cell Receptors

Safa Aouinti,

Affiliations IMGT, the international ImMunoGeneTics information system, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Institut de Génétique Humaine IGH, UPR CNRS 1142, Montpellier University, Montpellier cedex 5, France, Higher School of Statistics and Information Analysis, University of Carthage, Tunis, Tunisia, National School of Engineers of Tunis, Information Technology and Communications Department, Laboratory U2S, University of Tunis El-Manar, Tunis, Tunisia
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Dhafer Malouche,

Affiliations Higher School of Statistics and Information Analysis, University of Carthage, Tunis, Tunisia, National School of Engineers of Tunis, Information Technology and Communications Department, Laboratory U2S, University of Tunis El-Manar, Tunis, Tunisia
⨯
Véronique Giudicelli,

Affiliation IMGT, the international ImMunoGeneTics information system, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Institut de Génétique Humaine IGH, UPR CNRS 1142, Montpellier University, Montpellier cedex 5, France
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Sofia Kossida ,

* E-mail: sofia.kossida@igh.cnrs.fr (SK); marie-paule.lefranc@igh.cnrs.fr (M-PL)

Affiliation IMGT, the international ImMunoGeneTics information system, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Institut de Génétique Humaine IGH, UPR CNRS 1142, Montpellier University, Montpellier cedex 5, France
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Marie-Paule Lefranc

* E-mail: sofia.kossida@igh.cnrs.fr (SK); marie-paule.lefranc@igh.cnrs.fr (M-PL)

Affiliation IMGT, the international ImMunoGeneTics information system, Laboratoire d’ImmunoGénétique Moléculaire LIGM, Institut de Génétique Humaine IGH, UPR CNRS 1142, Montpellier University, Montpellier cedex 5, France
⨯

IMGT/HighV-QUEST Statistical Significance of IMGT Clonotype (AA) Diversity per Gene for Standardized Comparisons of Next Generation Sequencing Immunoprofiles of Immunoglobulins and T Cell Receptors

Safa Aouinti,
Dhafer Malouche,
Véronique Giudicelli,
Sofia Kossida,
Marie-Paule Lefranc

Published: November 5, 2015
https://doi.org/10.1371/journal.pone.0142353

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