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Open Access
Peer-reviewed
Research Article
Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases
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Tudor I. Oprea,
Affiliations Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America, Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Larry A. Sklar,
Affiliations Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America, Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America, University of New Mexico Center for Molecular Discovery, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Jacob O. Agola,
Current address: Jacob O. Agola, School of Engineering Center of Micro-Engineered Materials, MSC01 1120, University of New Mexico, Albuquerque, New Mexico, United States of America
Affiliation Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Yuna Guo,
Affiliations Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America, Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Melina Silberberg,
Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Joshua Roxby,
Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Anna Vestling,
Affiliation Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Elsa Romero,
Affiliation Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Zurab Surviladze,
Affiliations Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America, University of New Mexico Center for Molecular Discovery, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Cristina Murray-Krezan,
Affiliation Division of Epidemiology, Biostatistics, and Preventive Medicine, Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Anna Waller,
Affiliations Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America, University of New Mexico Center for Molecular Discovery, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Oleg Ursu,
Affiliation Translational Informatics Division, Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Laurie G. Hudson ,
¶‡ These authors are co-senior authors on this work.
Affiliations Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America, Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Angela Wandinger-Ness
* E-mail: wness@unm.edu
¶‡ These authors are co-senior authors on this work.
Affiliations Comprehensive Cancer Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America, Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, United States of America
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Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases
- Tudor I. Oprea,
- Larry A. Sklar,
- Jacob O. Agola,
- Yuna Guo,
- Melina Silberberg,
- Joshua Roxby,
- Anna Vestling,
- Elsa Romero,
- Zurab Surviladze,
- Cristina Murray-Krezan
- Published: November 11, 2015
- https://doi.org/10.1371/journal.pone.0142182