A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma

Paul A. Stewart; Katja Parapatics; Eric A. Welsh; André C. Müller; Haoyun Cao; Bin Fang; John M. Koomen; Steven A. Eschrich; Keiryn L. Bennett; Eric B. Haura

doi:10.1371/journal.pone.0142162

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Open Access

Peer-reviewed

Research Article

A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma

Paul A. Stewart,

Affiliation Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America 33612
⨯
Katja Parapatics,

Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, 1090 Vienna, Austria
⨯
Eric A. Welsh,

Affiliation Cancer Informatics Core Facility, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America 33612
⨯
André C. Müller,

Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, 1090 Vienna, Austria
⨯
Haoyun Cao,

Affiliation Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America 33612
⨯
Bin Fang,

Affiliation Proteomics Core Facility, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America 33612
⨯
John M. Koomen,

Affiliations Proteomics Core Facility, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America 33612, Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America 33612
⨯
Steven A. Eschrich,

Affiliations Cancer Informatics Core Facility, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America 33612, Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America 33612
⨯
Keiryn L. Bennett,

Affiliation CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, 1090 Vienna, Austria
⨯
Eric B. Haura

* E-mail: Eric.Haura@moffitt.org

Affiliation Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America 33612
⨯

A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma

Paul A. Stewart,
Katja Parapatics,
Eric A. Welsh,
André C. Müller,
Haoyun Cao,
Bin Fang,
John M. Koomen,
Steven A. Eschrich,
Keiryn L. Bennett,
Eric B. Haura

Published: November 5, 2015
https://doi.org/10.1371/journal.pone.0142162

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Protein expression
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Non-small cell lung cancer
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Adenocarcinoma
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Lung and intrathoracic tumors
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