Salinomycin Promotes Anoikis and Decreases the CD44+/CD24- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells

Hyunsook An; Ji Young Kim; Eunhye Oh; Nahyun Lee; Youngkwan Cho; Jae Hong Seo

doi:10.1371/journal.pone.0141919

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Research Article

Salinomycin Promotes Anoikis and Decreases the CD44⁺/CD24^- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells

Hyunsook An ,

Contributed equally to this work with: Hyunsook An, Ji Young Kim

Affiliations Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea, Brain Korea 21 Program for Biomedicine Science, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea
⨯
Ji Young Kim ,

Contributed equally to this work with: Hyunsook An, Ji Young Kim

Affiliations Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea, Brain Korea 21 Program for Biomedicine Science, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea
⨯
Eunhye Oh,

Affiliations Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea, Brain Korea 21 Program for Biomedicine Science, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea
⨯
Nahyun Lee,

Affiliations Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea, Brain Korea 21 Program for Biomedicine Science, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea
⨯
Youngkwan Cho,

Affiliations Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea, Brain Korea 21 Program for Biomedicine Science, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea
⨯
Jae Hong Seo

* E-mail: cancer@korea.ac.kr

Affiliations Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea, Brain Korea 21 Program for Biomedicine Science, Korea University College of Medicine, Korea University, Seoul 152–703, Republic of Korea
⨯

Salinomycin Promotes Anoikis and Decreases the CD44⁺/CD24^- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells

Hyunsook An,
Ji Young Kim,
Eunhye Oh,
Nahyun Lee,
Youngkwan Cho,
Jae Hong Seo

Published: November 3, 2015
https://doi.org/10.1371/journal.pone.0141919

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