Nitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor Cells

• Nilesh K. Sharma ,

  Contributed equally to this work with: Nilesh K. Sharma, Ashutosh Kumar

  Current address: Department of Molecular Biology and Genetics, Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Pune, MH, India

  Affiliation Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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• Ashutosh Kumar ,

  Contributed equally to this work with: Nilesh K. Sharma, Ashutosh Kumar

  Affiliation Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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• Amrita Kumari,

  Affiliation Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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• Erik J. Tokar,

  Affiliation National Toxicology Program, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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• Michael P. Waalkes,

  Affiliation National Toxicology Program, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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• Carl D. Bortner,

  Affiliation Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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• Jason Williams,

  Affiliation Laboratory of Structural Biology, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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• Marilyn Ehrenshaft,

  Affiliation Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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• Ronald P. Mason,

  Affiliation Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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• Birandra K. Sinha

  * E-mail: sinha1@niehs.nih.gov

  Affiliation Immunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle, Park, Durham, North Carolina, United States of America

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