Comparative Genome of GK and Wistar Rats Reveals Genetic Basis of Type 2 Diabetes

Tiancheng Liu; Hong Li; Guohui Ding; Zhen Wang; Yunqin Chen; Lei Liu; Yuanyuan Li; Yixue Li

doi:10.1371/journal.pone.0141859

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Open Access

Peer-reviewed

Research Article

Comparative Genome of GK and Wistar Rats Reveals Genetic Basis of Type 2 Diabetes

Tiancheng Liu ,

Contributed equally to this work with: Tiancheng Liu, Hong Li

Affiliation Key Lab of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
⨯
Hong Li ,

Contributed equally to this work with: Tiancheng Liu, Hong Li

Affiliation Key Lab of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
⨯
Guohui Ding,

Affiliations Key Lab of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Shanghai Center for Bioinformation Technology, Shanghai, China
⨯
Zhen Wang,

Affiliation Key Lab of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
⨯
Yunqin Chen,

Affiliation Shanghai Center for Bioinformation Technology, Shanghai, China
⨯
Lei Liu,

Affiliation Key Lab of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
⨯
Yuanyuan Li ,

* E-mail: yxli@sibs.ac.cn (YXL); yyli@scbit.org (YYL)

Affiliation Shanghai Center for Bioinformation Technology, Shanghai, China
⨯
Yixue Li

* E-mail: yxli@sibs.ac.cn (YXL); yyli@scbit.org (YYL)

Affiliations Key Lab of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Shanghai Center for Bioinformation Technology, Shanghai, China
⨯

Comparative Genome of GK and Wistar Rats Reveals Genetic Basis of Type 2 Diabetes

Tiancheng Liu,
Hong Li,
Guohui Ding,
Zhen Wang,
Yunqin Chen,
Lei Liu,
Yuanyuan Li,
Yixue Li

Published: November 3, 2015
https://doi.org/10.1371/journal.pone.0141859

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Type 2 diabetes
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Genomics
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Homozygosity
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Wistar rats
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Insulin signaling
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