Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines

Maricla Galetti; Pier Giorgio Petronini; Claudia Fumarola; Daniele Cretella; Silvia La Monica; Mara Bonelli; Andrea Cavazzoni; Francesca Saccani; Cristina Caffarra; Roberta Andreoli; Antonio Mutti; Marcello Tiseo; Andrea Ardizzoni; Roberta R. Alfieri

doi:10.1371/journal.pone.0141795

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Open Access

Peer-reviewed

Research Article

Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines

Maricla Galetti,

Affiliations Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy, Italian Workers’ Compensation Authority (INAIL), Research Centre at the University of Parma, Parma, Italy
⨯
Pier Giorgio Petronini ,

* E-mail: piergiorgio.petronini@unipr.it

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Claudia Fumarola,

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Daniele Cretella,

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Silvia La Monica,

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Mara Bonelli,

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Andrea Cavazzoni,

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Francesca Saccani,

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Cristina Caffarra,

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Roberta Andreoli,

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯
Antonio Mutti,

Affiliations Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy, Italian Workers’ Compensation Authority (INAIL), Research Centre at the University of Parma, Parma, Italy
⨯
Marcello Tiseo,

Affiliation Division of Medical Oncology, University Hospital of Parma, Parma, Italy
⨯
Andrea Ardizzoni,

Affiliation Medical Oncology Unit, S. Orsola-Malpighi Hospital, Bologna, Italy
⨯
Roberta R. Alfieri

* E-mail: piergiorgio.petronini@unipr.it

Affiliation Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy
⨯

Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines

Maricla Galetti,
Pier Giorgio Petronini,
Claudia Fumarola,
Daniele Cretella,
Silvia La Monica,
Mara Bonelli,
Andrea Cavazzoni,
Francesca Saccani,
Cristina Caffarra,
Roberta Andreoli

Published: November 4, 2015
https://doi.org/10.1371/journal.pone.0141795

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