Analysis of PIK3CA Mutations and Activation Pathways in Triple Negative Breast Cancer

Paolo Cossu-Rocca; Sandra Orrù; Maria Rosaria Muroni; Francesca Sanges; Giovanni Sotgiu; Sara Ena; Giovanna Pira; Luciano Murgia; Alessandra Manca; Maria Gabriela Uras; Maria Giuseppina Sarobba; Silvana Urru; Maria Rosaria De Miglio

doi:10.1371/journal.pone.0141763

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Open Access

Peer-reviewed

Research Article

Analysis of PIK3CA Mutations and Activation Pathways in Triple Negative Breast Cancer

Paolo Cossu-Rocca ,

Contributed equally to this work with: Paolo Cossu-Rocca, Sandra Orrù

* E-mail: pcossurocca@yahoo.it

Current Address: Department of Diagnostic Services, Surgical Pathology Unit, “Giovanni Paolo II” Hospital, ASL Olbia, Olbia, Italy

Affiliation Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy
⨯
Sandra Orrù ,

Contributed equally to this work with: Paolo Cossu-Rocca, Sandra Orrù

Affiliation Department of Pathology, “A. Businco” Oncologic Hospital, ASL Cagliari, Cagliari, Italy
⨯
Maria Rosaria Muroni,

Affiliation Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy
⨯
Francesca Sanges,

Affiliation Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy
⨯
Giovanni Sotgiu,

Affiliation Epidemiology and Medical Statistics Unit, Department of Biomedical Sciences, University of Sassari, Research, Medical Education and Professional Development Unit, AOU Sassari, Sassari, Italy
⨯
Sara Ena,

Affiliation Department of Biomedical Sciences, University of Sassari, Sassari, Italy
⨯
Giovanna Pira,

Affiliation Department of Biomedical Sciences, University of Sassari, Sassari, Italy
⨯
Luciano Murgia,

Affiliation Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy
⨯
Alessandra Manca,

Affiliation Department of Pathology, AOU Sassari, Sassari, Italy
⨯
Maria Gabriela Uras,

Affiliation Department of Pathology, AOU Sassari, Sassari, Italy
⨯
Maria Giuseppina Sarobba,

Affiliation Department of Medical Oncology, ASL Nuoro, Nuoro, Italy
⨯
Silvana Urru,

Affiliation Biomedicine Sector, Center for Advanced Studies, Research and Development in Sardinia Technology Park Polaris, Cagliari, Italy
⨯
Maria Rosaria De Miglio

Affiliation Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy
⨯

Analysis of PIK3CA Mutations and Activation Pathways in Triple Negative Breast Cancer

Paolo Cossu-Rocca,
Sandra Orrù,
Maria Rosaria Muroni,
Francesca Sanges,
Giovanni Sotgiu,
Sara Ena,
Giovanna Pira,
Luciano Murgia,
Alessandra Manca,
Maria Gabriela Uras

Published: November 5, 2015
https://doi.org/10.1371/journal.pone.0141763

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Cancers and neoplasms
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MAPK signaling cascades
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