Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease

Sofia Esteves; Sara Duarte-Silva; Luana Naia; Andreia Neves-Carvalho; Andreia Teixeira-Castro; Ana Cristina Rego; Anabela Silva-Fernandes; Patrícia Maciel

doi:10.1371/journal.pone.0141610

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Open Access

Peer-reviewed

Research Article

Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease

Sofia Esteves,

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710–057 Braga, Portugal, ICVS/3Bs—PT Government Associate Laboratory, Braga/Guimarães, Portugal
⨯
Sara Duarte-Silva,

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710–057 Braga, Portugal, ICVS/3Bs—PT Government Associate Laboratory, Braga/Guimarães, Portugal
⨯
Luana Naia,

Affiliations CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
⨯
Andreia Neves-Carvalho,

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710–057 Braga, Portugal, ICVS/3Bs—PT Government Associate Laboratory, Braga/Guimarães, Portugal
⨯
Andreia Teixeira-Castro,

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710–057 Braga, Portugal, ICVS/3Bs—PT Government Associate Laboratory, Braga/Guimarães, Portugal
⨯
Ana Cristina Rego,

Affiliations CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
⨯
Anabela Silva-Fernandes,

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710–057 Braga, Portugal, ICVS/3Bs—PT Government Associate Laboratory, Braga/Guimarães, Portugal
⨯
Patrícia Maciel

* E-mail: pmaciel@ecsaude.uminho.pt

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, 4710–057 Braga, Portugal, ICVS/3Bs—PT Government Associate Laboratory, Braga/Guimarães, Portugal
⨯

Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease

Sofia Esteves,
Sara Duarte-Silva,
Luana Naia,
Andreia Neves-Carvalho,
Andreia Teixeira-Castro,
Ana Cristina Rego,
Anabela Silva-Fernandes,
Patrícia Maciel

Published: October 27, 2015
https://doi.org/10.1371/journal.pone.0141610

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