Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells

Juan-Hua Quan; Jia-Qi Chu; Jaeyul Kwon; In-Wook Choi; Hassan Ahmed Hassan Ahmed Ismail; Wei Zhou; Guang-Ho Cha; Yu Zhou; Jae-Min Yuk; Eun-Kyeong Jo; Young-Ha Lee

doi:10.1371/journal.pone.0141550

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Open Access

Peer-reviewed

Research Article

Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells

Juan-Hua Quan ,

Contributed equally to this work with: Juan-Hua Quan, Jia-Qi Chu, Jaeyul Kwon

Affiliation Department of Gastroenterology, The Affiliated Hospital of Guangdong Medical College, Zhanjiang 524-001, Guangdong, China
⨯
Jia-Qi Chu ,

Contributed equally to this work with: Juan-Hua Quan, Jia-Qi Chu, Jaeyul Kwon

Affiliation Stem Cell Research and Cellular Therapy Center, The Affiliated Hospital of Guangdong Medical College, Zhanjiang, 524-001, China
⨯
Jaeyul Kwon ,

Contributed equally to this work with: Juan-Hua Quan, Jia-Qi Chu, Jaeyul Kwon

Affiliation Department of Medical Education, Chungnam National University School of Medicine, Daejeon, 301-131, Korea
⨯
In-Wook Choi,

Affiliation Department of Infection Biology, Chungnam National University School of Medicine, Daejeon, 301-131, Korea
⨯
Hassan Ahmed Hassan Ahmed Ismail,

Affiliation Department of Infection Biology, Chungnam National University School of Medicine, Daejeon, 301-131, Korea
⨯
Wei Zhou,

Affiliation Department of Infection Biology, Chungnam National University School of Medicine, Daejeon, 301-131, Korea
⨯
Guang-Ho Cha,

Affiliation Department of Infection Biology, Chungnam National University School of Medicine, Daejeon, 301-131, Korea
⨯
Yu Zhou,

Affiliation Department of Gastroenterology, The Affiliated Hospital of Guangdong Medical College, Zhanjiang 524-001, Guangdong, China
⨯
Jae-Min Yuk,

Affiliation Department of Infection Biology, Chungnam National University School of Medicine, Daejeon, 301-131, Korea
⨯
Eun-Kyeong Jo,

Affiliation Department of Microbiology and Infection Signaling Network Research Center, Chungnam National University School of Medicine, Daejeon, 301-131, Korea
⨯
Young-Ha Lee

* E-mail: yhalee@cnu.ac.kr

Affiliation Department of Infection Biology, Chungnam National University School of Medicine, Daejeon, 301-131, Korea
⨯

Intracellular Networks of the PI3K/AKT and MAPK Pathways for Regulating Toxoplasma gondii-Induced IL-23 and IL-12 Production in Human THP-1 Cells

Juan-Hua Quan,
Jia-Qi Chu,
Jaeyul Kwon,
In-Wook Choi,
Hassan Ahmed Hassan Ahmed Ismail,
Wei Zhou,
Guang-Ho Cha,
Yu Zhou,
Jae-Min Yuk,
Eun-Kyeong Jo

Published: November 3, 2015
https://doi.org/10.1371/journal.pone.0141550

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MAPK signaling cascades
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Small interfering RNA
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