A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART

Carmen Elena Gómez; Beatriz Perdiguero; Juan García-Arriaza; Victoria Cepeda; Carlos Óscar Sánchez-Sorzano; Beatriz Mothe; José Luis Jiménez; María Ángeles Muñoz-Fernández; Jose M. Gatell; Juan Carlos López Bernaldo de Quirós; Christian Brander; Felipe García; Mariano Esteban

doi:10.1371/journal.pone.0141456

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Peer-reviewed

Research Article

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART

Carmen Elena Gómez,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Beatriz Perdiguero,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Juan García-Arriaza,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Victoria Cepeda,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Carlos Óscar Sánchez-Sorzano,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Beatriz Mothe,

Affiliation IrsiCaixa-HIVACAT, Hospital Universitari Germans Trias i Pujol, Autonomous University of Barcelona, Badalona, Spain
⨯
José Luis Jiménez,

Affiliation Hospital Universitario Gregorio Marañón, Madrid, Spain
⨯
María Ángeles Muñoz-Fernández,

Affiliation Hospital Universitario Gregorio Marañón, Madrid, Spain
⨯
Jose M. Gatell,

Affiliation Hospital Clinic-HIVACAT, IDIBAPS, Barcelona, Spain
⨯
Juan Carlos López Bernaldo de Quirós,

Affiliation Hospital Universitario Gregorio Marañón, Madrid, Spain
⨯
Christian Brander,

Affiliations IrsiCaixa-HIVACAT, Hospital Universitari Germans Trias i Pujol, Autonomous University of Barcelona, Badalona, Spain, Institució Catalana de Recerca i Estudis Avancats (ICREA), Barcelona, and University of Vic and Central Catalonia, Vic, Spain
⨯
Felipe García,

Affiliation Hospital Clinic-HIVACAT, IDIBAPS, Barcelona, Spain
⨯
Mariano Esteban

* E-mail: mesteban@cnb.csic.es

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART

Carmen Elena Gómez,
Beatriz Perdiguero,
Juan García-Arriaza,
Victoria Cepeda,
Carlos Óscar Sánchez-Sorzano,
Beatriz Mothe,
José Luis Jiménez,
María Ángeles Muñoz-Fernández,
Jose M. Gatell,
Juan Carlos López Bernaldo de Quirós

Published: November 6, 2015
https://doi.org/10.1371/journal.pone.0141456

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