Epigenetics and Preeclampsia: Defining Functional Epimutations in the Preeclamptic Placenta Related to the TGF-β Pathway

Elizabeth Martin; Paul D. Ray; Lisa Smeester; Matthew R. Grace; Kim Boggess; Rebecca C. Fry

doi:10.1371/journal.pone.0141294

Loading metrics

Open Access

Peer-reviewed

Research Article

Epigenetics and Preeclampsia: Defining Functional Epimutations in the Preeclamptic Placenta Related to the TGF-β Pathway

Elizabeth Martin,

Affiliation Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, 135 Dauer Drive, CB 7431, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Paul D. Ray,

Affiliations Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, 135 Dauer Drive, CB 7431, University of North Carolina, Chapel Hill, North Carolina, United States of America, Curriculum in Toxicology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Lisa Smeester,

Affiliation Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, 135 Dauer Drive, CB 7431, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Matthew R. Grace,

Affiliation Department of Obstetrics & Gynecology, University of North Carolina School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Kim Boggess,

Affiliation Department of Obstetrics & Gynecology, University of North Carolina School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Rebecca C. Fry

* E-mail: rfry@unc.edu

Affiliations Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, 135 Dauer Drive, CB 7431, University of North Carolina, Chapel Hill, North Carolina, United States of America, Curriculum in Toxicology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯

Epigenetics and Preeclampsia: Defining Functional Epimutations in the Preeclamptic Placenta Related to the TGF-β Pathway

Elizabeth Martin,
Paul D. Ray,
Lisa Smeester,
Matthew R. Grace,
Kim Boggess,
Rebecca C. Fry

Published: October 28, 2015
https://doi.org/10.1371/journal.pone.0141294

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

DNA methylation
Is the Subject Area "DNA methylation" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Preeclampsia
Is the Subject Area "Preeclampsia" applicable to this article?

Thanks for your feedback.
Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.
DNA transcription
Is the Subject Area "DNA transcription" applicable to this article?

Thanks for your feedback.
Placenta
Is the Subject Area "Placenta" applicable to this article?

Thanks for your feedback.
Treatment guidelines
Is the Subject Area "Treatment guidelines" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.