Targeting Integrin-Dependent Adhesion and Signaling with 3-Arylquinoline and 3-Aryl-2-Quinolone Derivatives: A new Class of Integrin Antagonists

Open Access

Peer-reviewed

Research Article

Sandrine Fiorucci,

Affiliations Université Grenoble Alpes, Grenoble, France, INSERM, Centre de recherche U823, Grenoble, France
⨯
Xiaochen Lin,

Affiliation University of Connecticut, Storrs, United States of America
⨯
Karin Sadoul,

Affiliations Université Grenoble Alpes, Grenoble, France, INSERM, Centre de recherche U823, Grenoble, France
⨯
Guy Fournet,

Affiliation Université Claude Bernard-Lyon 1, Lyon, France
⨯
Daniel Bouvard,

Affiliations Université Grenoble Alpes, Grenoble, France, INSERM, Centre de recherche U823, Grenoble, France
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Olga Vinogradova,

Affiliation University of Connecticut, Storrs, United States of America
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Benoît Joseph,

Affiliation Université Claude Bernard-Lyon 1, Lyon, France
⨯
Marc R. Block

* E-mail: marc.block@ujf-grenoble.fr

Affiliations Université Grenoble Alpes, Grenoble, France, INSERM, Centre de recherche U823, Grenoble, France
⨯

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Integrins
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Drug interactions
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Platelet aggregation
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Cell adhesion
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Drug dependence
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Platelets
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Platelet activation
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Signal inhibition
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