Synthesis and Biological Evaluation of Novel Gigantol Derivatives as Potential Agents in Prevention of Diabetic Cataract

Jie Wu; Chuanjun Lu; Xue Li; Hua Fang; Wencheng Wan; Qiaohong Yang; Xiaosheng Sun; Meiling Wang; Xiaohong Hu; C.-Y. Oliver Chen; Xiaoyong Wei

doi:10.1371/journal.pone.0141092

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Open Access

Peer-reviewed

Research Article

Synthesis and Biological Evaluation of Novel Gigantol Derivatives as Potential Agents in Prevention of Diabetic Cataract

Jie Wu ,

Contributed equally to this work with: Jie Wu, Chuanjun Lu

Affiliation School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
⨯
Chuanjun Lu ,

Contributed equally to this work with: Jie Wu, Chuanjun Lu

Affiliations College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310014, China, Institute of Drug Synthesis and Pharmaceutical Processing, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China
⨯
Xue Li,

Affiliation School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
⨯
Hua Fang,

Affiliation School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
⨯
Wencheng Wan,

Affiliation School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
⨯
Qiaohong Yang,

Affiliation School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
⨯
Xiaosheng Sun,

Affiliation School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
⨯
Meiling Wang,

Affiliation School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
⨯
Xiaohong Hu,

Affiliation School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China
⨯
C.-Y. Oliver Chen,

Affiliation Antioxidants Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, 02111, United States of America
⨯
Xiaoyong Wei

* E-mail: jidewowxy@163.com

Affiliations School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China, Antioxidants Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, 02111, United States of America
⨯

Synthesis and Biological Evaluation of Novel Gigantol Derivatives as Potential Agents in Prevention of Diabetic Cataract

Jie Wu,
Chuanjun Lu,
Xue Li,
Hua Fang,
Wencheng Wan,
Qiaohong Yang,
Xiaosheng Sun,
Meiling Wang,
Xiaohong Hu,
C.-Y. Oliver Chen

Published: October 30, 2015
https://doi.org/10.1371/journal.pone.0141092

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