An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis

Brian W. Busser; Yongshun Lin; Yanqin Yang; Jun Zhu; Guokai Chen; Alan M. Michelson

doi:10.1371/journal.pone.0141066

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Peer-reviewed

Research Article

An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis

Brian W. Busser ,

* E-mail: michelsonam@nhlbi.nih.gov (AMM); brian.busser@cellectis.com (BWB)

Current address: Cellectis Inc., New York, NY, 10010, United States of America

Affiliation Systems Biology Center, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America
⨯
Yongshun Lin,

Affiliation Center for Molecular Medicine, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America
⨯
Yanqin Yang,

Affiliation Systems Biology Center, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America
⨯
Jun Zhu,

Affiliation Systems Biology Center, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America
⨯
Guokai Chen,

Current address: Faculty of Health Sciences, University of Macau, Taipa, Macau, China

Affiliation Center for Molecular Medicine, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America
⨯
Alan M. Michelson

* E-mail: michelsonam@nhlbi.nih.gov (AMM); brian.busser@cellectis.com (BWB)

Affiliation Systems Biology Center, Division of Intramural Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, 20892, United States of America
⨯

An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis

Brian W. Busser,
Yongshun Lin,
Yanqin Yang,
Jun Zhu,
Guokai Chen,
Alan M. Michelson

Published: October 20, 2015
https://doi.org/10.1371/journal.pone.0141066

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Gene expression
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Cell differentiation
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Drosophila melanogaster
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Gene regulation
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Histones
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Epigenetics
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Genetic screens
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Invertebrate genomics
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