Effects of the Interactions between Dust Exposure and Genetic Polymorphisms in Nalp3, Caspase-1, and IL-1β on the Risk of Silicosis: A Case-Control Study

Shaofan Weng; Lihua Wang; Yi Rong; Yuewei Liu; Xin Wang; Hongyu Guan; Weihong Chen

doi:10.1371/journal.pone.0140952

Loading metrics

Open Access

Peer-reviewed

Research Article

Effects of the Interactions between Dust Exposure and Genetic Polymorphisms in Nalp3, Caspase-1, and IL-1β on the Risk of Silicosis: A Case-Control Study

Shaofan Weng ,

Contributed equally to this work with: Shaofan Weng, Lihua Wang

Affiliations Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China, Shenzhen Prevention and Treatment Center for Occupational Disease, Shenzhen, Guangdong, China
⨯
Lihua Wang ,

Contributed equally to this work with: Shaofan Weng, Lihua Wang

Affiliations Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China, Shenzhen Baoan Center for Disease Control and Prevention, Shenzhen, Guangdong, China
⨯
Yi Rong,

Affiliation Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Yuewei Liu,

Affiliation Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Xin Wang,

Affiliation Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Hongyu Guan,

Affiliation Daye Iron Mine Hospital, Wuhan Iron and Steel Corporation, Huangshi, Hubei, China
⨯
Weihong Chen

* E-mail: wchen@mails.tjmu.edu.cn

Affiliation Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯

Effects of the Interactions between Dust Exposure and Genetic Polymorphisms in Nalp3, Caspase-1, and IL-1β on the Risk of Silicosis: A Case-Control Study

Shaofan Weng,
Lihua Wang,
Yi Rong,
Yuewei Liu,
Xin Wang,
Hongyu Guan,
Weihong Chen

Published: October 23, 2015
https://doi.org/10.1371/journal.pone.0140952

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Silicosis
Is the Subject Area "Silicosis" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Dust
Is the Subject Area "Dust" applicable to this article?

Thanks for your feedback.
Cancer risk factors
Is the Subject Area "Cancer risk factors" applicable to this article?

Thanks for your feedback.
Public and occupational health
Is the Subject Area "Public and occupational health" applicable to this article?

Thanks for your feedback.
Variant genotypes
Is the Subject Area "Variant genotypes" applicable to this article?

Thanks for your feedback.
Type 2 diabetes risk
Is the Subject Area "Type 2 diabetes risk" applicable to this article?

Thanks for your feedback.
Social systems
Is the Subject Area "Social systems" applicable to this article?

Thanks for your feedback.