Predicting Pharmacodynamic Drug-Drug Interactions through Signaling Propagation Interference on Protein-Protein Interaction Networks

Open Access

Peer-reviewed

Research Article

Kyunghyun Park,

Affiliation Department of Bio and Brain Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 305–701, Republic of Korea
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Docyong Kim,

Affiliation Department of Bio and Brain Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 305–701, Republic of Korea
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Suhyun Ha,

Affiliation Department of Bio and Brain Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 305–701, Republic of Korea
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Doheon Lee

* E-mail: dhlee@kaist.ac.kr

Affiliations Department of Bio and Brain Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 305–701, Republic of Korea, Bio-Synergy Research Center, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 305–701, Republic of Korea
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Drug discovery
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Adverse reactions
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Drug interactions
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Genetic interference
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Protein interaction networks
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Signaling networks
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Drug research and development
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Protein-protein interactions
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