Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs Suppress Inflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation and Reduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats

• Jing Zhao ,

  Contributed equally to this work with: Jing Zhao, Yongshan Mou

  Affiliations Department of Neurology, Jinan Central Hospital affiliated with Shandong University, 105 Jiefang Road, Jinan, Shandong, 250013, P. R. China, Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• Yongshan Mou ,

  Contributed equally to this work with: Jing Zhao, Yongshan Mou

  Affiliation Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• Joshua D. Bernstock,

  Affiliation Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• Dace Klimanis,

  Affiliation Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• Sixian Wang,

  Affiliation College of Arts and Sciences, Cornell University, Ithaca, New York, United States of America

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• Maria Spatz,

  Affiliation Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• Dragan Maric,

  Affiliation National Institute of Neurological Disorders and Stroke, Flow Cytometry Core Facility, Bethesda, Maryland, United States of America

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• Kory Johnson,

  Affiliation Information Technology & Bioinformatics Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• Dennis M. Klinman,

  Affiliation Cancer and Inflammation Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Xiaohong Li ,

  * E-mail: hallenbj@ninds.nih.gov (JMH); lixinh@mail.nih.gov (Xinhui Li); xiaohong-li@sdu.edu.cn (Xiaohong Li)

  Affiliation Department of Neurology, Jinan Central Hospital affiliated with Shandong University, 105 Jiefang Road, Jinan, Shandong, 250013, P. R. China

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• Xinhui Li ,

  * E-mail: hallenbj@ninds.nih.gov (JMH); lixinh@mail.nih.gov (Xinhui Li); xiaohong-li@sdu.edu.cn (Xiaohong Li)

  Affiliation Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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• John M. Hallenbeck

  * E-mail: hallenbj@ninds.nih.gov (JMH); lixinh@mail.nih.gov (Xinhui Li); xiaohong-li@sdu.edu.cn (Xiaohong Li)

  Affiliation Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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