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Open Access

Peer-reviewed

Research Article

Prostate Cancer Heterogeneous High-Metastatic Multi-Organ-Colonizing Chemo-Resistant Variants Selected by Serial Metastatic Passage in Nude Mice Are Highly Enriched for Multinucleate Giant Cells

Lei Zhang,

Affiliation AntiCancer Inc., San Diego, CA, United States of America
⨯
Chengyu Wu ,

* E-mail: chengyu720@yahoo.com.cn (CW); all@anticancer.com (RMH)

Affiliation Department of Traditional Chinese Medicine, Nanjing University of Traditional Chinese Medicine, Nanjing, PR China
⨯
Robert M. Hoffman

* E-mail: chengyu720@yahoo.com.cn (CW); all@anticancer.com (RMH)

Affiliations AntiCancer Inc., San Diego, CA, United States of America, Department of Surgery, University of California San Diego, San Diego, CA, United States of America
⨯

Prostate Cancer Heterogeneous High-Metastatic Multi-Organ-Colonizing Chemo-Resistant Variants Selected by Serial Metastatic Passage in Nude Mice Are Highly Enriched for Multinucleate Giant Cells

Lei Zhang,
Chengyu Wu,
Robert M. Hoffman

x

Published: November 4, 2015
https://doi.org/10.1371/journal.pone.0140721

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Metastasis
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Prostate cancer
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Giant cells
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Lymph nodes
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Lung and intrathoracic tumors
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Mouse models
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Traditional Chinese medicine
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