Systematic Evaluation of Genetic Variants for Polycystic Ovary Syndrome in a Chinese Population

Yuping Xu; Zhiqiang Li; Fenglian Ai; Jianhua Chen; Qiong Xing; Ping Zhou; Zhaolian Wei; Yongyong Shi; Xiao-Jin He; Yunxia Cao

doi:10.1371/journal.pone.0140695

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Open Access

Peer-reviewed

Research Article

Systematic Evaluation of Genetic Variants for Polycystic Ovary Syndrome in a Chinese Population

Yuping Xu,

Affiliations Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China, Institute of Reproductive Genetics, Anhui Medical University, Hefei, 230022, China, Anhui Provincial Engineering Technology Research Center for Biopreservation and Artificial Organs, Hefei, 230022, China
⨯
Zhiqiang Li,

Affiliation The Bio-X Institutes, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, 200030, China
⨯
Fenglian Ai,

Affiliations Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China, Institute of Reproductive Genetics, Anhui Medical University, Hefei, 230022, China, Anhui Provincial Engineering Technology Research Center for Biopreservation and Artificial Organs, Hefei, 230022, China
⨯
Jianhua Chen,

Affiliation The Bio-X Institutes, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, 200030, China
⨯
Qiong Xing,

Affiliations Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China, Institute of Reproductive Genetics, Anhui Medical University, Hefei, 230022, China, Anhui Provincial Engineering Technology Research Center for Biopreservation and Artificial Organs, Hefei, 230022, China
⨯
Ping Zhou,

Affiliations Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China, Institute of Reproductive Genetics, Anhui Medical University, Hefei, 230022, China, Anhui Provincial Engineering Technology Research Center for Biopreservation and Artificial Organs, Hefei, 230022, China
⨯
Zhaolian Wei,

Affiliations Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China, Institute of Reproductive Genetics, Anhui Medical University, Hefei, 230022, China, Anhui Provincial Engineering Technology Research Center for Biopreservation and Artificial Organs, Hefei, 230022, China
⨯
Yongyong Shi ,

* E-mail: caoyunxia6@126.com (YC); shiyongyong@gmail.com (YS); hxj0117@126.com (XH)

Affiliation The Bio-X Institutes, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, 200030, China
⨯
Xiao-Jin He ,

* E-mail: caoyunxia6@126.com (YC); shiyongyong@gmail.com (YS); hxj0117@126.com (XH)

Affiliations Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China, Institute of Reproductive Genetics, Anhui Medical University, Hefei, 230022, China, Anhui Provincial Engineering Technology Research Center for Biopreservation and Artificial Organs, Hefei, 230022, China
⨯
Yunxia Cao

* E-mail: caoyunxia6@126.com (YC); shiyongyong@gmail.com (YS); hxj0117@126.com (XH)

Affiliations Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China, Institute of Reproductive Genetics, Anhui Medical University, Hefei, 230022, China, Anhui Provincial Engineering Technology Research Center for Biopreservation and Artificial Organs, Hefei, 230022, China
⨯

Systematic Evaluation of Genetic Variants for Polycystic Ovary Syndrome in a Chinese Population

Yuping Xu,
Zhiqiang Li,
Fenglian Ai,
Jianhua Chen,
Qiong Xing,
Ping Zhou,
Zhaolian Wei,
Yongyong Shi,
Xiao-Jin He,
Yunxia Cao

Published: October 16, 2015
https://doi.org/10.1371/journal.pone.0140695

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Polycystic ovary syndrome
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Genome-wide association studies
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Haplotypes
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Introns
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Single nucleotide polymorphisms
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Chinese people
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Genetic loci
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Glucose
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