A Grape Seed Procyanidin Extract Ameliorates Fructose-Induced Hypertriglyceridemia in Rats via Enhanced Fecal Bile Acid and Cholesterol Excretion and Inhibition of Hepatic Lipogenesis

Laura E. Downing; Rebecca M. Heidker; Gianella C. Caiozzi; Brian S. Wong; Kelvin Rodriguez; Fernando Del Rey; Marie-Louise Ricketts

doi:10.1371/journal.pone.0140267

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A Grape Seed Procyanidin Extract Ameliorates Fructose-Induced Hypertriglyceridemia in Rats via Enhanced Fecal Bile Acid and Cholesterol Excretion and Inhibition of Hepatic Lipogenesis

Laura E. Downing ,

Contributed equally to this work with: Laura E. Downing, Rebecca M. Heidker, Gianella C. Caiozzi

Affiliation Department of Agriculture, Nutrition and Veterinary Sciences, University of Nevada Reno, Reno, Nevada, United States of America
⨯
Rebecca M. Heidker ,

Contributed equally to this work with: Laura E. Downing, Rebecca M. Heidker, Gianella C. Caiozzi

Affiliation Department of Agriculture, Nutrition and Veterinary Sciences, University of Nevada Reno, Reno, Nevada, United States of America
⨯
Gianella C. Caiozzi ,

Contributed equally to this work with: Laura E. Downing, Rebecca M. Heidker, Gianella C. Caiozzi

Current address: Hospital de Urgencia Asistencia Pública, Santiago, Chile

Affiliation Department of Agriculture, Nutrition and Veterinary Sciences, University of Nevada Reno, Reno, Nevada, United States of America
⨯
Brian S. Wong,

Affiliation Department of Agriculture, Nutrition and Veterinary Sciences, University of Nevada Reno, Reno, Nevada, United States of America
⨯
Kelvin Rodriguez,

Affiliation Department of Agriculture, Nutrition and Veterinary Sciences, University of Nevada Reno, Reno, Nevada, United States of America
⨯
Fernando Del Rey,

Affiliation Department of Agriculture, Nutrition and Veterinary Sciences, University of Nevada Reno, Reno, Nevada, United States of America
⨯
Marie-Louise Ricketts

* E-mail: mricketts@cabnr.unr.edu

Affiliation Department of Agriculture, Nutrition and Veterinary Sciences, University of Nevada Reno, Reno, Nevada, United States of America
⨯

A Grape Seed Procyanidin Extract Ameliorates Fructose-Induced Hypertriglyceridemia in Rats via Enhanced Fecal Bile Acid and Cholesterol Excretion and Inhibition of Hepatic Lipogenesis

Laura E. Downing,
Rebecca M. Heidker,
Gianella C. Caiozzi,
Brian S. Wong,
Kelvin Rodriguez,
Fernando Del Rey,
Marie-Louise Ricketts

Published: October 12, 2015
https://doi.org/10.1371/journal.pone.0140267

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