Study of Malformin C, a Fungal Source Cyclic Pentapeptide, as an Anti-Cancer Drug

Jing Wang; Zaoli Jiang; Wing Lam; Elizabeth A. Gullen; Zhe Yu; Ying Wei; Lihui Wang; Caroline Zeiss; Amanda Beck; Ee-Chun Cheng; Chunfu Wu; Yung-Chi Cheng; Yixuan Zhang

doi:10.1371/journal.pone.0140069

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Open Access

Peer-reviewed

Research Article

Study of Malformin C, a Fungal Source Cyclic Pentapeptide, as an Anti-Cancer Drug

Jing Wang ,

Contributed equally to this work with: Jing Wang, Zaoli Jiang

Affiliations Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Oncology and Hematology, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China
⨯
Zaoli Jiang ,

Contributed equally to this work with: Jing Wang, Zaoli Jiang

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Wing Lam,

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Elizabeth A. Gullen,

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Zhe Yu,

Affiliation School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China
⨯
Ying Wei,

Affiliation School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China
⨯
Lihui Wang,

Affiliation School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China
⨯
Caroline Zeiss,

Affiliation Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Amanda Beck,

Affiliation Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Ee-Chun Cheng,

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Chunfu Wu,

Affiliation School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China
⨯
Yung-Chi Cheng ,

* E-mail: yccheng@yale.edu (YCC); zhangyxzsh@163.com (YZ)

Affiliation Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Yixuan Zhang

* E-mail: yccheng@yale.edu (YCC); zhangyxzsh@163.com (YZ)

Affiliation School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China
⨯

Study of Malformin C, a Fungal Source Cyclic Pentapeptide, as an Anti-Cancer Drug

Jing Wang,
Zaoli Jiang,
Wing Lam,
Elizabeth A. Gullen,
Zhe Yu,
Ying Wei,
Lihui Wang,
Caroline Zeiss,
Amanda Beck,
Ee-Chun Cheng

Published: November 5, 2015
https://doi.org/10.1371/journal.pone.0140069

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