ERK Signaling Is Essential for Macrophage Development

Edward T. Richardson; Supriya Shukla; Nancy Nagy; W. Henry Boom; Rose C. Beck; Lan Zhou; Gary E. Landreth; Clifford V. Harding

doi:10.1371/journal.pone.0140064

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Peer-reviewed

Research Article

ERK Signaling Is Essential for Macrophage Development

Edward T. Richardson,

Affiliations Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Medical Scientist Training Program, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Supriya Shukla,

Affiliation Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Nancy Nagy,

Affiliation Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
W. Henry Boom,

Affiliations Division of Infectious Diseases and HIV Medicine, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Rose C. Beck,

Affiliation Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Lan Zhou,

Affiliation Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯
Gary E. Landreth,

Affiliation Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Clifford V. Harding

* E-mail: cvh3@cwru.edu

Affiliations Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Division of Infectious Diseases and HIV Medicine, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
⨯

ERK Signaling Is Essential for Macrophage Development

Edward T. Richardson,
Supriya Shukla,
Nancy Nagy,
W. Henry Boom,
Rose C. Beck,
Lan Zhou,
Gary E. Landreth,
Clifford V. Harding

Published: October 7, 2015
https://doi.org/10.1371/journal.pone.0140064

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Macrophages
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Bone marrow cells
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ERK signaling cascade
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Monocytes
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Genetically modified animals
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Neutrophils
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Cell differentiation
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Flow cytometry
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