Improved Production Efficiency of Virus-Like Particles by the Baculovirus Expression Vector System

Javier López-Vidal; Silvia Gómez-Sebastián; Juan Bárcena; Maria del Carmen Nuñez; Diego Martínez-Alonso; Benoit Dudognon; Eva Guijarro; José M. Escribano

doi:10.1371/journal.pone.0140039

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Open Access

Peer-reviewed

Research Article

Improved Production Efficiency of Virus-Like Particles by the Baculovirus Expression Vector System

Javier López-Vidal ,

Contributed equally to this work with: Javier López-Vidal, Silvia Gómez-Sebastián

Affiliation Alternative Gene Expression S.L. (ALGENEX), Edificio de empresas, Campus Montegancedo (Universidad Politécnica de Madrid), Pozuelo de Alarcón, Madrid, Spain
⨯
Silvia Gómez-Sebastián ,

Contributed equally to this work with: Javier López-Vidal, Silvia Gómez-Sebastián

Affiliation Alternative Gene Expression S.L. (ALGENEX), Edificio de empresas, Campus Montegancedo (Universidad Politécnica de Madrid), Pozuelo de Alarcón, Madrid, Spain
⨯
Juan Bárcena,

Affiliation Centro de Investigación en Sanidad Animal (CISA-INIA), Valdeolmos, Madrid, Spain
⨯
Maria del Carmen Nuñez,

Affiliation Alternative Gene Expression S.L. (ALGENEX), Edificio de empresas, Campus Montegancedo (Universidad Politécnica de Madrid), Pozuelo de Alarcón, Madrid, Spain
⨯
Diego Martínez-Alonso,

Affiliation Alternative Gene Expression S.L. (ALGENEX), Edificio de empresas, Campus Montegancedo (Universidad Politécnica de Madrid), Pozuelo de Alarcón, Madrid, Spain
⨯
Benoit Dudognon,

Affiliation Alternative Gene Expression S.L. (ALGENEX), Edificio de empresas, Campus Montegancedo (Universidad Politécnica de Madrid), Pozuelo de Alarcón, Madrid, Spain
⨯
Eva Guijarro,

Affiliation Departamento de Biotecnología, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Autovia A6 Km 7, Madrid, Spain
⨯
José M. Escribano

* E-mail: escriban@inia.es

Affiliation Departamento de Biotecnología, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Autovia A6 Km 7, Madrid, Spain
⨯

Improved Production Efficiency of Virus-Like Particles by the Baculovirus Expression Vector System

Javier López-Vidal,
Silvia Gómez-Sebastián,
Juan Bárcena,
Maria del Carmen Nuñez,
Diego Martínez-Alonso,
Benoit Dudognon,
Eva Guijarro,
José M. Escribano

Published: October 12, 2015
https://doi.org/10.1371/journal.pone.0140039

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Baculoviruses
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Recombinant proteins
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Tuberculosis
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Protein expression
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