Alum Adjuvant Enhances Protection against Respiratory Syncytial Virus but Exacerbates Pulmonary Inflammation by Modulating Multiple Innate and Adaptive Immune Cells

Ki-Hye Kim; Young-Tae Lee; Hye Suk Hwang; Young-Man Kwon; Yu-Jin Jung; Youri Lee; Jong Seok Lee; Yu-Na Lee; Soojin Park; Sang-Moo Kang

doi:10.1371/journal.pone.0139916

Loading metrics

Open Access

Peer-reviewed

Research Article

Alum Adjuvant Enhances Protection against Respiratory Syncytial Virus but Exacerbates Pulmonary Inflammation by Modulating Multiple Innate and Adaptive Immune Cells

Ki-Hye Kim,

Affiliation Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America
⨯
Young-Tae Lee,

Affiliation Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America
⨯
Hye Suk Hwang,

Affiliation Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America
⨯
Young-Man Kwon,

Affiliation Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America
⨯
Yu-Jin Jung,

Affiliation Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America
⨯
Youri Lee,

Affiliation Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America
⨯
Jong Seok Lee,

Affiliations Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America, National Institute of Biological Resources, Incheon, Gyeonggi-do, South Korea
⨯
Yu-Na Lee,

Affiliation Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America
⨯
Soojin Park,

Affiliation Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America
⨯
Sang-Moo Kang

* E-mail: skang24@gsu.edu

Affiliation Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States of America
⨯

Alum Adjuvant Enhances Protection against Respiratory Syncytial Virus but Exacerbates Pulmonary Inflammation by Modulating Multiple Innate and Adaptive Immune Cells

Ki-Hye Kim,
Young-Tae Lee,
Hye Suk Hwang,
Young-Man Kwon,
Yu-Jin Jung,
Youri Lee,
Jong Seok Lee,
Yu-Na Lee,
Soojin Park,
Sang-Moo Kang

Published: October 15, 2015
https://doi.org/10.1371/journal.pone.0139916

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Alumni
Is the Subject Area "Alumni" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Antibodies
Is the Subject Area "Antibodies" applicable to this article?

Thanks for your feedback.
Immunologic adjuvants
Is the Subject Area "Immunologic adjuvants" applicable to this article?

Thanks for your feedback.
Enzyme-linked immunoassays
Is the Subject Area "Enzyme-linked immunoassays" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
T helper cells
Is the Subject Area "T helper cells" applicable to this article?

Thanks for your feedback.