PDL1 Expression on Plasma and Dendritic Cells in Myeloma Bone Marrow Suggests Benefit of Targeted anti PD1-PDL1 Therapy

Anne-Marit Sponaas; Neda Nejati Moharrami; Emadoldin Feyzi; Therese Standal; Even Holth Rustad; Anders Waage; Anders Sundan

doi:10.1371/journal.pone.0139867

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Open Access

Peer-reviewed

Research Article

PDL1 Expression on Plasma and Dendritic Cells in Myeloma Bone Marrow Suggests Benefit of Targeted anti PD1-PDL1 Therapy

Anne-Marit Sponaas ,

* E-mail: anne-marit.sponaas@ntnu.no

Affiliation KG Jebsen Centre for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway
⨯
Neda Nejati Moharrami,

Affiliations KG Jebsen Centre for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, CEMIR, Centre of Molecular Immune Regulation, Norwegian University of Science and Technology, Trondheim, Norway
⨯
Emadoldin Feyzi,

Affiliations KG Jebsen Centre for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, Department of Hematology, St.Olavs University Hospital, Trondheim, Norway
⨯
Therese Standal,

Affiliations KG Jebsen Centre for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, CEMIR, Centre of Molecular Immune Regulation, Norwegian University of Science and Technology, Trondheim, Norway
⨯
Even Holth Rustad,

Affiliations KG Jebsen Centre for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, Department of Hematology, St.Olavs University Hospital, Trondheim, Norway
⨯
Anders Waage,

Affiliations KG Jebsen Centre for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, Department of Hematology, St.Olavs University Hospital, Trondheim, Norway
⨯
Anders Sundan

Affiliations KG Jebsen Centre for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, CEMIR, Centre of Molecular Immune Regulation, Norwegian University of Science and Technology, Trondheim, Norway
⨯

PDL1 Expression on Plasma and Dendritic Cells in Myeloma Bone Marrow Suggests Benefit of Targeted anti PD1-PDL1 Therapy

Anne-Marit Sponaas,
Neda Nejati Moharrami,
Emadoldin Feyzi,
Therese Standal,
Even Holth Rustad,
Anders Waage,
Anders Sundan

Published: October 7, 2015
https://doi.org/10.1371/journal.pone.0139867

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