Mitochondrial DNA Polymerase POLG1 Disease Mutations and Germline Variants Promote Tumorigenic Properties

• Bhupendra Singh,

  Affiliation Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, United States of America

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• Kjerstin M. Owens,

  Affiliation Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY, United States of America

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• Prachi Bajpai,

  Affiliation Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, United States of America

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• Mohamed Mokhtar Desouki,

  Affiliation Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN, United States of America

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• Vinodh Srinivasasainagendra,

  Affiliation Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, United States of America

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• Hemant K. Tiwari,

  Affiliation Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, United States of America

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• Keshav K. Singh

  * E-mail: kksingh@uab.edu

  Affiliations Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, United States of America, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Department of Environmental Health, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Center for Aging, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, UAB Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, Birmingham Veterans Affairs Medical Center, Birmingham, AL, 35294, United States of America

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