Intraovarian Transplantation of Female Germline Stem Cells Rescue Ovarian Function in Chemotherapy-Injured Ovaries

Jiaqiang Xiong; Zhiyong Lu; Meng Wu; Jinjin Zhang; Jing Cheng; Aiyue Luo; Wei Shen; Li Fang; Su Zhou; Shixuan Wang

doi:10.1371/journal.pone.0139824

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Open Access

Peer-reviewed

Research Article

Intraovarian Transplantation of Female Germline Stem Cells Rescue Ovarian Function in Chemotherapy-Injured Ovaries

Jiaqiang Xiong ,

Contributed equally to this work with: Jiaqiang Xiong, Zhiyong Lu

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Zhiyong Lu ,

Contributed equally to this work with: Jiaqiang Xiong, Zhiyong Lu

Affiliations Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China, Hubei Key Laboratory of Embryonic Stem Cell Research, Tai-He Hospital, Hubei University of Medicine, Shiyan, Hubei, China
⨯
Meng Wu,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Jinjin Zhang,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Jing Cheng,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Aiyue Luo,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Wei Shen,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Li Fang,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Su Zhou,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Shixuan Wang

* E-mail: sxwang@tjh.tjmu.edu.cn

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯

Intraovarian Transplantation of Female Germline Stem Cells Rescue Ovarian Function in Chemotherapy-Injured Ovaries

Jiaqiang Xiong,
Zhiyong Lu,
Meng Wu,
Jinjin Zhang,
Jing Cheng,
Aiyue Luo,
Wei Shen,
Li Fang,
Su Zhou,
Shixuan Wang

Published: October 2, 2015
https://doi.org/10.1371/journal.pone.0139824

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Transfection
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Cancer treatment
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Female infertility
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Oocytes
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Stem cell therapy
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