CUL4-DDB1-CDT2 E3 Ligase Regulates the Molecular Clock Activity by Promoting Ubiquitination-Dependent Degradation of the Mammalian CRY1

Open Access

Peer-reviewed

Research Article

Xin Tong,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Deqiang Zhang,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Anirvan Guha,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Blake Arthurs,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Victor Cazares,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Neil Gupta,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Lei Yin

* E-mail: leiyin@umich.edu

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯

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Ligases
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Ubiquitination
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Circadian oscillators
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Circadian rhythms
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293T cells
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Immunoblotting
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Transfection
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Hepatocytes
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