In vitro Characterization of the Rapid Cytotoxicity of Anticancer Peptide HPRP-A2 through Membrane Destruction and Intracellular Mechanism against Gastric Cancer Cell Lines

Open Access

Peer-reviewed

Research Article

Jing Zhao,

Affiliations Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China, School of Life Sciences, Jilin University, Changchun, China
⨯
Xueyu Hao,

Affiliations Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China, School of Life Sciences, Jilin University, Changchun, China
⨯
Dong Liu,

Affiliations Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China, School of Life Sciences, Jilin University, Changchun, China
⨯
Yibing Huang ,

* E-mail: huangyibing@jlu.edu.cn (YBH); chen_yuxin@jlu.edu.cn (YXC)

Affiliations Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China, School of Life Sciences, Jilin University, Changchun, China, National Engineering Laboratory for AIDS Vaccine, Jilin University, Changchun, China
⨯
Yuxin Chen

* E-mail: huangyibing@jlu.edu.cn (YBH); chen_yuxin@jlu.edu.cn (YXC)

Affiliations Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, Jilin University, Changchun, China, School of Life Sciences, Jilin University, Changchun, China, National Engineering Laboratory for AIDS Vaccine, Jilin University, Changchun, China
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Cancer treatment
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Gastric cancer
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Cell membranes
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Apoptosis
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Membrane potential
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Flow cytometry
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Cytotoxicity
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Intracellular membranes
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