Scutellarin’s Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-Iα

Lin Li; Lu Li; Chen Chen; Jian Yang; Jiaxun Li; Na Hu; Yang Li; Dongmei Zhang; Tao Guo; Xuan Liu; Weimin Yang

doi:10.1371/journal.pone.0139570

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Open Access

Peer-reviewed

Research Article

Scutellarin’s Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-Iα

Lin Li ,

Contributed equally to this work with: Lin Li, Lu Li

Affiliations School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China, Department of Cardiology, First Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Lu Li ,

Contributed equally to this work with: Lin Li, Lu Li

Affiliations School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
⨯
Chen Chen,

Affiliation School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China
⨯
Jian Yang,

Affiliation School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China
⨯
Jiaxun Li,

Affiliation School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China
⨯
Na Hu,

Affiliation School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China
⨯
Yang Li,

Affiliation School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China
⨯
Dongmei Zhang,

Affiliation Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
⨯
Tao Guo,

Affiliation Department of Cardiology, First Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Xuan Liu ,

* E-mail: ywmbessie@yeah.net (WY); xuanliu@simm.ac.cn (XL)

Affiliation Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
⨯
Weimin Yang

* E-mail: ywmbessie@yeah.net (WY); xuanliu@simm.ac.cn (XL)

Affiliation School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China
⨯

Scutellarin’s Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-Iα

Lin Li,
Lu Li,
Chen Chen,
Jian Yang,
Jiaxun Li,
Na Hu,
Yang Li,
Dongmei Zhang,
Tao Guo,
Xuan Liu

Published: October 6, 2015
https://doi.org/10.1371/journal.pone.0139570

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Endothelium
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Heart
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MTT assay
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