Defense of Elevated Body Weight Setpoint in Diet-Induced Obese Rats on Low Energy Diet Is Mediated by Loss of Melanocortin Sensitivity in the Paraventricular Hypothalamic Nucleus

• Dirk W. Luchtman,

  Current address: Department of Neurology, Focus Program Translational Neurosciences, Rhein-Main Neuroscience Network, Johannes Gutenberg University Mainz, 55131 Mainz, Germany

  Affiliation Department of Pharmacology and Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada

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• Melissa J. S. Chee,

  Current address: Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

  Affiliation Department of Pharmacology and Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada

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• Barbora Doslikova,

  Affiliation Department of Pharmacology and Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada

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• Daniel L. Marks,

  Affiliation Papé Family Pediatric Research Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd. Portland, Oregon, United States of America

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• Vickie E. Baracos,

  Affiliation Department of Oncology, University of Alberta, Edmonton, Alberta, Canada

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• William F. Colmers

  * E-mail: william.colmers@ualberta.ca

  Affiliation Department of Pharmacology and Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada

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