Subcellular Partitioning of Protein Tyrosine Phosphatase 1B to the Endoplasmic Reticulum and Mitochondria Depends Sensitively on the Composition of Its Tail Anchor

Julia Fueller; Mikhail V. Egorov; Kirstin A. Walther; Ola Sabet; Jana Mallah; Markus Grabenbauer; Ali Kinkhabwala

doi:10.1371/journal.pone.0139429

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Peer-reviewed

Research Article

Subcellular Partitioning of Protein Tyrosine Phosphatase 1B to the Endoplasmic Reticulum and Mitochondria Depends Sensitively on the Composition of Its Tail Anchor

Julia Fueller,

Affiliations Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany, Center for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, Im Neuenheimer Feld 282, 69120, Heidelberg, Germany
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Mikhail V. Egorov,

Affiliations Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany, Institute of Anatomy and Cell Biology, Heidelberg University, Im Neuenheimer Feld 307, 69120, Heidelberg, Germany
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Kirstin A. Walther,

Affiliation Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany
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Ola Sabet,

Affiliation Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany
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Jana Mallah,

Affiliation Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany
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Markus Grabenbauer,

Affiliations Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany, Institute of Anatomy and Cell Biology, Heidelberg University, Im Neuenheimer Feld 307, 69120, Heidelberg, Germany
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Ali Kinkhabwala

* E-mail: alikink@gmail.com

Affiliation Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany
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Subcellular Partitioning of Protein Tyrosine Phosphatase 1B to the Endoplasmic Reticulum and Mitochondria Depends Sensitively on the Composition of Its Tail Anchor

Julia Fueller,
Mikhail V. Egorov,
Kirstin A. Walther,
Ola Sabet,
Jana Mallah,
Markus Grabenbauer,
Ali Kinkhabwala

Published: October 2, 2015
https://doi.org/10.1371/journal.pone.0139429

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25 Feb 2016
09:56 GMT
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Objection to claim of NOVELTY that PTP1B is localised to the mitochondria in mammalian cells Posted by mmcgee on 24 Feb 2016 at 12:57 GMT

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