The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5’ End of SS-Overhang Cleavage

Open Access

Peer-reviewed

Research Article

Hyun-Suk Kim,

Affiliation Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
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Sung-Kyung Kim,

Affiliation Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Robert Hromas,

Affiliation Department of Medicine, University of Florida and Shands Health Care System, Gainesville, Florida, United States of America
⨯
Suk-Hee Lee

* E-mail: slee@iu.edu

Affiliations Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Indiana University Simon Cancer Center, Indianapolis, Indiana, United States of America
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DNA cleavage
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DNA replication
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Deletion mutagenesis
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DNA repair
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DNA damage
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DNA denaturation
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Non-homologous end joining
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Recombinase polymerase amplification
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