Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito

Lixin Wang; Sachiko Mogami; Seiichi Yakabi; Hiroshi Karasawa; Chihiro Yamada; Koji Yakabi; Tomohisa Hattori; Yvette Taché

doi:10.1371/journal.pone.0139325

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Open Access

Peer-reviewed

Research Article

Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito

Lixin Wang ,

* E-mail: lixinw@ucla.edu

Affiliation CURE/Digestive Diseases Center and Center for Neurobiology of Stress, Department of Medicine, Digestive Diseases Division, University of California at Los Angeles, and VA Greater Los Angeles Health Care System, Los Angeles, California, United States of America
⨯
Sachiko Mogami,

Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan
⨯
Seiichi Yakabi,

Current address: Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan

Affiliation CURE/Digestive Diseases Center and Center for Neurobiology of Stress, Department of Medicine, Digestive Diseases Division, University of California at Los Angeles, and VA Greater Los Angeles Health Care System, Los Angeles, California, United States of America
⨯
Hiroshi Karasawa,

Current address: Cardiovascular-Metabolic Research Laboratories, Daiichi Sankyo Co., Ltd. 1-2-58, Hiromachi, Shinagawa-ku, Tokyo, Japan

Affiliation CURE/Digestive Diseases Center and Center for Neurobiology of Stress, Department of Medicine, Digestive Diseases Division, University of California at Los Angeles, and VA Greater Los Angeles Health Care System, Los Angeles, California, United States of America
⨯
Chihiro Yamada,

Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan
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Koji Yakabi,

Affiliation Department of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, Saitama, Japan
⨯
Tomohisa Hattori,

Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan
⨯
Yvette Taché

Affiliation CURE/Digestive Diseases Center and Center for Neurobiology of Stress, Department of Medicine, Digestive Diseases Division, University of California at Los Angeles, and VA Greater Los Angeles Health Care System, Los Angeles, California, United States of America
⨯

Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito

Lixin Wang,
Sachiko Mogami,
Seiichi Yakabi,
Hiroshi Karasawa,
Chihiro Yamada,
Koji Yakabi,
Tomohisa Hattori,
Yvette Taché

Published: September 30, 2015
https://doi.org/10.1371/journal.pone.0139325

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