ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection

Raoel Maan; Adriaan J. van der Meer; Willem Pieter Brouwer; Elisabeth P. C. Plompen; Milan J. Sonneveld; Robert Roomer; Annemiek A. van der Eijk; Zwier M. A. Groothuismink; Bettina E. Hansen; Bart J. Veldt; Harry L. A. Janssen; Andre Boonstra; Robert J. de Knegt

doi:10.1371/journal.pone.0139317

Loading metrics

Open Access

Peer-reviewed

Research Article

ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection

Raoel Maan ,

* E-mail: r.maan@erasmusmc.nl

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Adriaan J. van der Meer,

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Willem Pieter Brouwer,

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Elisabeth P. C. Plompen,

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Milan J. Sonneveld,

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Robert Roomer,

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Annemiek A. van der Eijk,

Affiliation Department of Viroscience, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Zwier M. A. Groothuismink,

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Bettina E. Hansen,

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Bart J. Veldt,

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Harry L. A. Janssen,

Affiliations Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands, Toronto Centre for Liver Disease, Toronto Western & General Hospital, University Health Network, Toronto, Canada
⨯
Andre Boonstra,

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯
Robert J. de Knegt

Affiliation Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands
⨯

ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection

Raoel Maan,
Adriaan J. van der Meer,
Willem Pieter Brouwer,
Elisabeth P. C. Plompen,
Milan J. Sonneveld,
Robert Roomer,
Annemiek A. van der Eijk,
Zwier M. A. Groothuismink,
Bettina E. Hansen,
Bart J. Veldt

Published: October 6, 2015
https://doi.org/10.1371/journal.pone.0139317

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Platelets
Is the Subject Area "Platelets" applicable to this article?

Thanks for your feedback.
Antiviral therapy
Is the Subject Area "Antiviral therapy" applicable to this article?

Thanks for your feedback.
Hepatitis C virus
Is the Subject Area "Hepatitis C virus" applicable to this article?

Thanks for your feedback.
Hemolytic anemia
Is the Subject Area "Hemolytic anemia" applicable to this article?

Thanks for your feedback.
Blood transfusion
Is the Subject Area "Blood transfusion" applicable to this article?

Thanks for your feedback.
Hemoglobin
Is the Subject Area "Hemoglobin" applicable to this article?

Thanks for your feedback.
Inosine
Is the Subject Area "Inosine" applicable to this article?

Thanks for your feedback.
Anemia
Is the Subject Area "Anemia" applicable to this article?

Thanks for your feedback.