Interactions of L-3,5,3'-Triiodothyronine, Allopregnanolone, and Ivermectin with the GABAA Receptor: Evidence for Overlapping Intersubunit Binding Modes

Open Access

Peer-reviewed

Research Article

Interactions of L-3,5,3'-Triiodothyronine, Allopregnanolone, and Ivermectin with the GABA_A Receptor: Evidence for Overlapping Intersubunit Binding Modes

Thomas Westergard,

Affiliations Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America, Center for Computational and Integrative Biology, Rutgers University-Camden, Camden, New Jersey, United States of America
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Reza Salari,

Affiliations Center for Computational and Integrative Biology, Rutgers University-Camden, Camden, New Jersey, United States of America, Department of Physics, Rutgers University-Camden, Camden, New Jersey, United States of America
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Joseph V. Martin,

Affiliations Center for Computational and Integrative Biology, Rutgers University-Camden, Camden, New Jersey, United States of America, Department of Biology, Rutgers University-Camden, Camden, New Jersey, United States of America
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Grace Brannigan

* E-mail: grace.brannigan@rutgers.edu

Affiliations Center for Computational and Integrative Biology, Rutgers University-Camden, Camden, New Jersey, United States of America, Department of Physics, Rutgers University-Camden, Camden, New Jersey, United States of America
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Molecular dynamics
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Biochemical simulations
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Hydrogen bonding
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Gamma-aminobutyric acid
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Transmembrane receptors
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Xenopus oocytes
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Oocytes
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Crystal structure
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