GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes

Open Access

Peer-reviewed

Research Article

Xi-Lin Chen,

Affiliation Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
⨯
Daniel Serrano,

Affiliation Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
⨯
Marian Mayhue,

Affiliation Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
⨯
Kasper Hoebe,

Affiliation Department of Pediatrics, Division of Cellular and Molecular Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States of America
⨯
Subburaj Ilangumaran,

Affiliations Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada, Centre de Recherche Clinique, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
⨯
Sheela Ramanathan

* E-mail: Sheela.Ramanathan@Usherbrooke.ca

Affiliations Immunology Division, Department of Pediatrics, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada, Centre de Recherche Clinique, Université de Sherbrooke, Sherbrooke, J1H 5N4, Québec, Canada
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T cells
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Phosphorylation
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Cross-linking
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Genetically modified animals
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TCR signaling cascade
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Mitochondria
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Phosphatases
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Guanosine triphosphatase
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