Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening

• Chiara Ruggeri,

  Affiliation Dipartimento di Scienze biochimiche "A. Rossi Fanelli", Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185, Roma, Italy

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• Nyssa Drinkwater,

  Affiliations Department of Microbiology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia, Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia

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• Komagal Kannan Sivaraman,

  Affiliations Department of Microbiology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia, Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia

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• Rebecca S. Bamert,

  Affiliations Department of Microbiology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia, Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia

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• Sheena McGowan ,

  Contributed equally to this work with: Sheena McGowan, Alessandro Paiardini

  * E-mail: sheena.mcgowan@monash.edu (SM); alessandro.paiardini@uniroma1.it (AP)

  Affiliations Department of Microbiology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia, Department of Biochemistry and Molecular Biology, Monash University, Clayton Campus, Melbourne, Victoria, 3800, Australia

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• Alessandro Paiardini

  Contributed equally to this work with: Sheena McGowan, Alessandro Paiardini

  * E-mail: sheena.mcgowan@monash.edu (SM); alessandro.paiardini@uniroma1.it (AP)

  Affiliation Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185, Roma, Italy

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