Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation

Paul J. Meakin; Vicky L. Morrison; Claire C. Sneddon; Terhi Savinko; Liisa Uotila; Susan M. Jalicy; Jennie L. Gabriel; Li Kang; Michael L. J. Ashford; Susanna C. Fagerholm

doi:10.1371/journal.pone.0138872

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Peer-reviewed

Research Article

Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation

Paul J. Meakin ,

Contributed equally to this work with: Paul J. Meakin, Vicky L. Morrison

Affiliation Divison of Cardiovascular & Diabetes Medicine, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom
⨯
Vicky L. Morrison ,

Contributed equally to this work with: Paul J. Meakin, Vicky L. Morrison

Affiliations Division of Cancer Research, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom, Institute of Biotechnology, University of Helsinki, Helsinki, Finland
⨯
Claire C. Sneddon,

Affiliation Divison of Cardiovascular & Diabetes Medicine, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom
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Terhi Savinko,

Affiliation Institute of Biotechnology, University of Helsinki, Helsinki, Finland
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Liisa Uotila,

Affiliation Institute of Biotechnology, University of Helsinki, Helsinki, Finland
⨯
Susan M. Jalicy,

Affiliation Divison of Cardiovascular & Diabetes Medicine, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom
⨯
Jennie L. Gabriel,

Affiliation Divison of Cardiovascular & Diabetes Medicine, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom
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Li Kang,

Affiliation Divison of Cardiovascular & Diabetes Medicine, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom
⨯
Michael L. J. Ashford ,

* E-mail: susanna.fagerholm@helsinki.fi (SCF); m.l.j.ashford@dundee.ac.uk (MLJA)

¶‡ MLJA and SCF are joint senior authors on this work.

Affiliation Divison of Cardiovascular & Diabetes Medicine, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom
⨯
Susanna C. Fagerholm

* E-mail: susanna.fagerholm@helsinki.fi (SCF); m.l.j.ashford@dundee.ac.uk (MLJA)

¶‡ MLJA and SCF are joint senior authors on this work.

Affiliations Division of Cancer Research, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom, Institute of Biotechnology, University of Helsinki, Helsinki, Finland
⨯

Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation

Paul J. Meakin,
Vicky L. Morrison,
Claire C. Sneddon,
Terhi Savinko,
Liisa Uotila,
Susan M. Jalicy,
Jennie L. Gabriel,
Li Kang,
Michael L. J. Ashford,
Susanna C. Fagerholm

Published: September 25, 2015
https://doi.org/10.1371/journal.pone.0138872

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Neutrophils
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