Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation

Open Access

Peer-reviewed

Research Article

Zhonghua Wang ,

* E-mail: wangz3@uthscsa.edu

Affiliation Department of Biochemistry, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, United States of America
⨯
Akash Bhattacharya,

Affiliation Department of Biochemistry, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, United States of America
⨯
Dmitri N. Ivanov

Affiliation Department of Biochemistry, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, United States of America
⨯

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Library screening
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Protein interactions
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Breast cancer
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Fluorescence polarization
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Messenger RNA
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NMR spectroscopy
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RNA-binding proteins
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Cancer treatment
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