Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine

Liliane Maria Fernandes de Oliveira; Mirian Galliote Morale; Agatha A. Muniz Chaves; Aline Marques Cavalher; Aline Soriano Lopes; Mariana de Oliveira Diniz; Alessandra Soares Schanoski; Robson Lopes de Melo; Luís Carlos de Souza Ferreira; Maria Leonor S. de Oliveira; Marilene Demasi; Paulo Lee Ho

doi:10.1371/journal.pone.0138686

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Open Access

Peer-reviewed

Research Article

Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine

Liliane Maria Fernandes de Oliveira ,

Contributed equally to this work with: Liliane Maria Fernandes de Oliveira, Mirian Galliote Morale

Affiliation Laboratório de Biotecnologia Molecular I, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯
Mirian Galliote Morale ,

Contributed equally to this work with: Liliane Maria Fernandes de Oliveira, Mirian Galliote Morale

Affiliation Laboratório de Biotecnologia Molecular I, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯
Agatha A. Muniz Chaves,

Affiliation Laboratório de Biotecnologia Molecular I, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯
Aline Marques Cavalher,

Affiliation Laboratório de Biotecnologia Molecular I, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯
Aline Soriano Lopes,

Affiliation Laboratório Especial de Toxinologia Aplicada-CeTICS, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯
Mariana de Oliveira Diniz,

Affiliation Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo-SP, Brazil
⨯
Alessandra Soares Schanoski,

Affiliation Laboratório de Biotecnologia Molecular I, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯
Robson Lopes de Melo,

Affiliation Laboratório Especial de Toxinologia Aplicada-CeTICS, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯
Luís Carlos de Souza Ferreira,

Affiliation Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo-SP, Brazil
⨯
Maria Leonor S. de Oliveira,

Affiliation Laboratório de Biotecnologia Molecular I, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯
Marilene Demasi,

Affiliation Laboratório de Bioquímica e Biofísica, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯
Paulo Lee Ho

* E-mail: paulo.ho@butantan.gov.br

Affiliation Laboratório de Biotecnologia Molecular I, Instituto Butantan, Av. Vital Brasil 1500, São Paulo-SP, Brazil
⨯

Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine

Liliane Maria Fernandes de Oliveira,
Mirian Galliote Morale,
Agatha A. Muniz Chaves,
Aline Marques Cavalher,
Aline Soriano Lopes,
Mariana de Oliveira Diniz,
Alessandra Soares Schanoski,
Robson Lopes de Melo,
Luís Carlos de Souza Ferreira,
Maria Leonor S. de Oliveira

Published: September 21, 2015
https://doi.org/10.1371/journal.pone.0138686

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